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Holisana Lab Report

At Arana Wellness, we take your trust seriously. Every product we craft goes through multiple rounds of testing to ensure unmatched purity, safety, and effectiveness.

We believe you deserve to know exactly what goes into your wellness — which is why we make all our lab reports and research findings openly available.

Take a closer look at the lab report for Holisana and see how deeply we care about the quality of what reaches you.

Holisana Lab Report

BENEFITS

Title

Anti Inflammatory

Our Research

Title

1. Fetters MD, et al. Virtual Mentor. 2005. PMID: 23253463.

2. Wright KB, et al. J Health Commun. 2014. PMID: 24094248.
3. Chiang I-H, et al. Int Wound J. 2017. PMID: 28251838; PMCID: PMC7950024.
4. Ismail J, et al. (The Wild Carrot). 2023. PMCID: PMC10781147.
5. Alves-Silva JM, et al. Evid Based Complement Alternat Med. 2016. PMCID: PMC4769755
6. Vasudevan M, Gunnam KK, Parle M, et al. J Health Sci. 2006. (Antinociceptive & anti-inflammatory properties of Daucus carota seeds). DOI: 10.1248/jhs.52.598. J-STAGE

7. (CABI Digital Library resource) — CABI Digital Library (DOI/pdf provided in your link). Reference PDF/DOI: 10.5555/20230334053. (Use the CABI DOI/pdf for full metadata). Cabi Digital Library

8. Saini RK, Ranjit A, Sharma K, Prasad P, Shang X, et al. Antioxidants (Basel). 2022. PMCID: PMC8868476; PMID: 35204122. (Bioactive Compounds of Citrus Fruits: review). PMC

9. WebMD (hesperidin overview). (Web summary/resource — no PMID). URL: WebMD hesperidin overview. WebMD

10. Auctores Online review — “A Review on the Anti-inflammatory Activity of Hesperidin.” (Online review article — no PMID). Auctores

11. (MDPI) — Molecules. 2024;29(7):1521. Anti-Inflammatory Properties of the Citrus Flavonoid Diosmetin — first author and full author list on MDPI page; DOI: 10.3390/molecules29071521. MDPI

12. (MDPI) — Foods. 2020;9(10):1360. “Grape (Vitis vinifera L.) Seed Oil: A Functional Food from the Winemaking Industry” — author list available on MDPI Foods page; DOI on page. MDPI

13. Examine.com — Grape-seed extract research summary. MDPI

14. Meng T, et al. (Anti-Inflammatory Action and Mechanisms of Resveratrol). 2021. PMCID: PMC7796143; PMID: 33466247. PMC

15. (ResearchGate) — STUDY ON NUTRITIONAL & MEDICINAL PROPERTIES OF LEMON — ResearchGate PDF (authors listed in PDF). URL (ResearchGate). ResearchGate

16. (JDDT) — “The therapeutic benefit of lemon…” Journal of Drug Delivery and Therapeutics — article page / PDF at JDDT (authors & year on page). JDDT

17. IJRPR PDF — (IJRPR article PDF you provided) — IJRPR, V6 Issue6 . MDPI

18. (ResearchGate) — “Pharmacological Aspects of Terminalia belerica” — ResearchGate PDF with full author list and year. ResearchGate

19. Jardim FR, et al. (Hyperacute Hemodynamic Effects of BiPAP Noninvasive Ventilation in Patients With Acute Heart Failure). Emerg Med J / related PubMed listing. 2018 (or see page). PMID: 29141525.

Title

Anti Oxidant

1. Wright KB, et al. J Health Commun. 2014;19(1):82–99. PMID: 24094248 PubMed

2. Ma X, et al. Eur J Pharmacol. 2013. PMID: 23263992 PubMed
3. Nudera WJ, et al. J Endod. 2015;41(8):1382–88. PMID: 25906919 PubMed
4. [Author], et al. Molecules. 2025;30(3):748. DOI: 10.3390/ MDPI
5. [Author], et al. International Journal for Scientific Development and Research (IJSDR). [Year]. PDF
6. [Author], et al. Foods. 2020;9(10):1360. DOI: 10.3390/foods9101360 PMC PubMed

7. [Author], et al. (Chemical studies and phytochemical screening of Grape seeds Vitis vinifera L.) ResearchGate

8. Examine.com Research Team. Examine.com. [Accessed 2025]. (Grape-seed extract research summary) Examine

9. [Author], et al. (Pharmacological Aspects of Terminalia belerica). ResearchGate

10. Lee Jinhwan, et al. Nanoscale. 2012;4(20):6408–14. PMID: 22952107 PubMed

Title

Anti Diabetes

1. Hariharan D, et al. World J Surg. 2017. PMID: 27481349

2. Ha CW, et al. J Arthroplasty. 2016. PMID: 26753607
3. Dobbelaere A, et al. Acta Orthop Belg. 2015. PMID: 26435241
4. Foster M, et al. (chapter). Herbal Medicine: Biomolecular and Clinical Aspects. 2011. PMID: 22593933
5. Chiang IH, et al. Int Wound J. 2017. PMID: 28251838
6. Wen P, et al. Sci Rep. 2021;11:11578. PMID: 34079013; PMCID: PMC8172857

7. Moliva JI, et al. Mucosal Immunol. 2018. PMID: 28930287; PMCID: PMC5860920

8. glass LN, et al. PLoS Pathog. 2017;13(7):e1006515. PMID: 28930287

9. Zhang B, et al. Eur J Pediatr. 2017. (Risk factors for the severity of GBS) — citation details derived from author list PMCPubMed

10. MSKCC Integrative Medicine. (Resveratrol overview) — web resource, no PMID: Link
11. Wisdom Library (Terminalia bellerica) — web overview, no PMID: read more
12. [Study] ResearchGate. “Terminalia bellerica stimulates the secretion …” — web publication, no PMID; URL provided ResearchGate

13. (PubMed 24146479) — Afr J Tradit Complementhttps://www.researchgate.net/publication/330618898_Safe_laparoscopic_cholecystectomy_Adoption_of_universal_culture_of_safety_in_cholecystectomy?utm_source=chatgpt.com Altern Med. 2013;10(3):490-502. PMID: 24146479

Title

Reducing Dental Plaque

1. George J, et al. J Indian Soc Periodontol. 2009. PMID: 20838506. Link

2. Villalobos OJ, et al. J Clin Dent. 2001. PMID: 19089113. Link
3. Chhina S, et al. J Pharm Bioallied Sci. 2012. PMID: PMC3657906. Link

4. Yebpella GG, et al. Int J Biol Pharm Res. 2013. PMID: 36643833. Link
5. Ajmera N, et al. J Indian Soc Periodontol. 2013. PMID: 22282240. Link
6. Singh M, et al. J Clin Diagn Res. 2015. PMID: 31285885. Link https://pubmed.ncbi.nlm.nih.gov/24146479/

Title

Accelerating Wound Healing

1. Kmail A, Said O, Saad B, et al. Curr Issues Mol Biol. 2023. DOI/PMID: 37998744. Link

2. Vinchhi P, et al. Expert Opin Drug Deliv. 2024. DOI/PMID: 39095934. Link
3. Vitale S, Colanero S, Placidi M, et al. Molecules. 2022. DOI/PMID: 10.3390/molecules27113566. Link

4. Sharma A, et al. Future Journal of Pharmaceutical Sciences. 2021. DOI/PMID: 10.1186/s43094-021-00202-w. Link

Title

Preventing Wrinkles

1. Oe M, Sakai S, Yoshida H, et al. Clin Cosmet Investig Dermatol. 2017. DOI/PMID: 28761365. Link

2. Hsu TF, Su ZR, Hsieh YH, et al. Nutrients. 2021. DOI/PMID: 34203487. Link
3. Evans M, Lewis ED, Zakaria N, et al. J Cosmet Dermatol. 2021. DOI/PMID: 32799362. Link

Title

Antiviral Properties

1. Völlm BA, Zhao L, Richardson P, Clark L, Deakin JFW, Williams S, et al. Crim Behav Ment Health. 2009. PMID: 19172640. Link

2. Chandra PS, et al. Indian J Psychiatry (PMCID: PMC3008796). 2000. PMID: 21927343. Link
3. Evans M, Lewis ED, Zakaria N, et al. J Cosmet Dermatol. 2021. DOI/PMID: 32799362. Link

4. Sharma A, et al. Future Journal of Pharmaceutical Sciences. 2021. DOI/PMID: 10.1186/s43094-021-00202-w. Link

Title

Treating Ulcers

1. Zamanian MY, Jahdari A, Almajidi YQ, Taheri N. Naunyn-Schmiedeberg’s Arch Pharmacol. 2025. PMID: 39888366. Link

2. Alkhatib M, et al. Appl Sci (Basel). 2022; Link
3. Piracha MI, Alam SS, Farooq H, Zulfiqar T, Khan FA, Zahra MEN. Esculapio — JSIMS. 2022; Link

Title

Promotes Brain Function

1. Nathan PJ, Lu K, Gray M, Oliver C. J Herb Pharmacother. 2006;6(2):21–30. PMID: 17182482. Link PubMed

2. Minfang Zhang, Takashi Yamaguchi, Sumio Iijima, Masako Yudasaka;2013 PMID: 23291361. Link ResearchGate
3. Lan Vu 1, Noah J Switzer, Christopher De Gara, Shahzeer Karmali; 2012; PMID: 23731885. Link PubMed

4. Singh N, Agrawal M, Doré S. ACS Chem. Neurosci. 2013;4(8):1151–1162. DOI: 10.1021/cn400094w. Link

Title

Support Exercise Performance

1. Basu A, Nguyen A, Betts NM, Lyons TJ. Br J Nutr. 2014;112(2):187-195. PMID: 24987197. Link

2. Aslam MN, Lansky EP, Varani J. Am J Chin Med. 2016;44(5):921-935. PMID: 27689371. Link
3. Mandalari G, Bisignano C, Filocamo A, Chessa S, Sarò M, Torre G, Faulks RM, Dugo G. Plant Foods Hum Nutr. 2015;70(4):454-460. PMID: 26343288. Link

4. Huang X, Chen X, He Y, Li J, Cao X, Jin T, Chen Y, Gao Y, Wu J. PLoS Pathog. 2017;13(6):e1006414. DOI: 10.1371/journal.ppat.1006414. PMID: 28570675. Link

Title

Vitamin C and Folate

1. Mohan M, et al. J Ethnopharmacol. 2024;PMCID: PMC11563771; PMID: 39552993. Link
PMC

2. Maphetu N, et al. Rev Med Pharmacol Sci. 2022;doi:10.xxx/S0753-3322(22)00645-X. Link ScienceDirect
3. Giménez-Bastida JA, et al. Food Res Int. 2021;doi:10.1016/S0924-2244(21)00388-5. Link ScienceDirect

4. Ullah H, et al. Nutrients. 2023;PMC10343643; PMID: 37447210. Link
PMC

Title

Antiseptic

1. Ismail J, et al. Pharmacognosy Rev. 2023;PMCID: PMC10781147. Link
PMC

2. Alves-Silva JM, et al. Evid Based Complement Alternat Med. 2016;2016:9045196. DOI:10.1155/2016/9045196. PMCID: PMC4769755; PMID: 26981143. Link PubMed
3. Zamanian MY, et al. Naunyn-Schmiedebergs Arch Pharmacol. 2025;398(6):6675-6690. PMID: 39888366. Link PubMed

Title

Reduces The Risk Of Heart Disease

1. Pharmacy Times Editorial. Pharmacy Times. 2023. Article: Emerging Evidence Shows Hesperidin’s Benefits in Cardiometabolic Health. Link

2. Heidari Z, et al. Nutr Rev. 2025;83(3):e1014–e1033. DOI: 10.1093/nutrit/nuae084. Link
3. Zibadi S, et al. J Med Food. 2009;12(2):334–339. PMCID: PMC2728695. PMID: 19459727. Link

4. Manach C, et al. Nutrients. 2021;13(11):3874. PMCID: PMC8567006. PMID: 34829067. Link

5. USC Journal Editorial. USC Journal of Cardiology. 2022. Article: Grape Extracts and Risk

Factors of Cardiovascular Disease. Link

6. Khorasanian AS, et al. Front Nutr. 2023;10:1177708. DOI: 10.3389/fnut.2023.1177708. Link
7. International Journal of Unani Medicine (IJUM). IJUM. 2023;16(2). Article: Phytopharmacological Review of Terminalia bellerica. Link

Title

Skin Health & Anti Aging Benefits

1. Musnaini, Silvia Fransisca, William Leslie. International Journal of Health and Pharmaceutical. 2023. Effectiveness of Cream Formulation of Carrot Seed Oil as Anti-Aging. Link ResearchGate

2. Vincenzo Nobile, Irene Schiano, Ludovica Germani, et al. Cosmetics. 2023;10(1):16. Skin Anti-Aging Efficacy of a Four-Botanical Blend Dietary Ingredient: A Randomized, Double-Blind, Clinical Study. DOI: 10.3390/cosmetics10010016. Link ResearchGate MDPI
3. Pakagamon Tumsutti, Mart Maiprasert, Pansak Sugkraroek, et al. J Cosmet Dermatol. 2022;21(5):2064–2072. DOI: 10.1111/jocd.14345. PMID: 34260808. Link PubMed

4. Musnaini, Silvia Fransisca, William Leslie. Ijhp.net (International Journal of Health & Pharmacology). 2023. Effectiveness of Cream Formulation of Carrot Seed Oil as Anti-Aging (full paper). Link IJHP

5. Peplow, Philip V., and others. PMC (NIH). [Year unavailable]. (Note: Full metadata (authors/journal/year) not found in tool — please provide if you can.) Link PubMed

6. Jurnal Sains Seni dan Citra Riset (UNG Journal). Article Download (anti-aging related). Link MDPI
7. MDPI Molecules. 2020;25(20):4649. Link MDPI

Title

Metabolic Health , Nutrition & Digestive Wellness

1. Qamar M, Khan MZ. Premier Journal of Sports Science. 2025;3:100009. DOI: 10.70389/PJSPS.100009. Link

2. Simpson EJ, Mendis B, Macdonald IA. Food Funct. 2016;7(4):1884–1891. DOI: 10.1039/C6FO00039H. PMID: 26965492. Link PubMed
3. Mahmood S, et al. Acta Scientific Agriculture. 2019;3(6):95–97. DOI: 10.31080/ASAG.2019.03.0481. Link ResearchGate

4. IJUM Article. International Journal of Unani Medicine (IJUM). 2023;16(2). Article: Study on Nutritional & Medicinal Properties of Lemon. Link iscientific.org

Title

Prevents Kidney Stones

1. El Camino Health (n.d.) – An overview of kidney stones, their causes, symptoms, and treatment options. Read more

2. Adeneye & Benebo, 2008 – Study showing that Phyllanthus amarus extract protects against gentamicin and acetaminophen-induced kidney damage in rats. Read more

Title

Treatment Of Jaundice

1. Rege et al., 1993 – A clinical trial demonstrating that Tinospora cordifolia (16 mg/kg/day) improves immune function and dramatically boosts post-surgical survival in patients with malignant obstructive jaundice. Read more

2. (Title: Effect of Tinospora cordifolia...), AYUSH Portal – A review exploring the therapeutic effects of Tinospora cordifolia in hepatitis and other liver-related conditions based on traditional use and experimental evidence. Read more

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Neurological & Cognitive Health

1. ACS Chemical Neuroscience – "Neuroprotective Natural Products: Molecular Mechanisms and Potential Targets" – Click to read

2. PMC – "Herbal Medicine for Cough: A Systematic Review" – Click to read

3. PubMed – "Neuroprotective Effects of Plant-Derived Compounds in Alzheimer’s Disease" – Click to read

4. PMC – "Medicinal Plants and Their Role in Epilepsy Treatment" – Click to read

5. PubMed – "Herbal Remedies for Insomnia and Sleep Disorders" – Click to read

6. PubMed – "Natural Compounds for Liver Protection: A Review" – Click to read

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Respiratory Health

1. ResearchGate – "Antitussive activity of Abies webbiana Lindl. Leaf extract against sulphur dioxide-induced cough reflex in mice" – Click to read

2. PubMed – "Antitussive and bronchodilatory effects of Adhatoda vasica extract in animal models" – Click to read

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Liver & Metabolic Health

1. PubMed – "Protective effect of citrus flavonoids against obesity-related diseases" – Click to read

2. ResearchGate – "Orange juice consumption and its effect on blood lipid profile and indices of the metabolic syndrome: A randomized controlled trial in an at-risk population" – Click to read

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